[HPforGrownups] Re: Magical Genetics

ksnidget at aol.com ksnidget at aol.com
Wed Sep 25 12:21:23 UTC 2002


No: HPFGUIDX 44459

Corinth wrote:

<<Dynamic mutation, right?  I hadn't considered something like that, but 
it makes much more sense that my propositions.  However, it still 
seems that there would be that a pesky recessive gene lurking on the 
other chromosome (I could be wrong, but it seems unlikely that both 
genes would reach the pivotal number of repeats at the same time). >>

These mutations are ALWAYS dominate mutations.  So no need
for both genes to reach critical length at the same time.

Dynamic sort of implies more of an active process than I am
really discussion.

There are many reasons for spontaneous mutation, repeated
DNA is ALWAYS a hot spot for things to slip a bit and get
copied wrong. The longer the repeat, the more likely this is
to happen.

In genes with long repeats the # of repeats may vary from
generation to generation.  Usually only by a few, but sometimes
by a critical amount that changes the function of the gene.

Why I stick with the dominate is muggle-wizard crosses
seem to only produce wizards in the F1 generation. That
indicates a dominate gene.

And most dominate gene diseases that are known do the
whole spontaneously arising in a totally unaffected family,
and rarely revert bad to the unaffected state. Which is 
what we also see in the books.

A continual supply of "new mutants" arising in the muggle
"unaffected" mutation.

Most of the patterns seen in disease states also occur in
mutations that do not cause disease, but cause a new
phenotype to arise.
Ksnidget.


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