[HPforGrownups] Re: Magical Genetics
ksnidget at aol.com
ksnidget at aol.com
Wed Sep 25 12:21:23 UTC 2002
No: HPFGUIDX 44459
Corinth wrote:
<<Dynamic mutation, right? I hadn't considered something like that, but
it makes much more sense that my propositions. However, it still
seems that there would be that a pesky recessive gene lurking on the
other chromosome (I could be wrong, but it seems unlikely that both
genes would reach the pivotal number of repeats at the same time). >>
These mutations are ALWAYS dominate mutations. So no need
for both genes to reach critical length at the same time.
Dynamic sort of implies more of an active process than I am
really discussion.
There are many reasons for spontaneous mutation, repeated
DNA is ALWAYS a hot spot for things to slip a bit and get
copied wrong. The longer the repeat, the more likely this is
to happen.
In genes with long repeats the # of repeats may vary from
generation to generation. Usually only by a few, but sometimes
by a critical amount that changes the function of the gene.
Why I stick with the dominate is muggle-wizard crosses
seem to only produce wizards in the F1 generation. That
indicates a dominate gene.
And most dominate gene diseases that are known do the
whole spontaneously arising in a totally unaffected family,
and rarely revert bad to the unaffected state. Which is
what we also see in the books.
A continual supply of "new mutants" arising in the muggle
"unaffected" mutation.
Most of the patterns seen in disease states also occur in
mutations that do not cause disease, but cause a new
phenotype to arise.
Ksnidget.
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