Importance of Death in Horcrux Making

[ongj87]

No: HPFGUIDX 136665

I'm a little confused on one part.  Who says that the murder has to be 
significant to make a horcrux?   Don't we know that Frank Bryce was 
the death that led to Voldemort making Nagini as horcrux?  And I'm 
certain that Frank Bryce wasn't at all significant to Voldemort, he 
was just another muggle to him.  Somebody please correct me if I'm 
wrong.

- ongj87